UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival

UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival

Hepatoblastoma (HB) is the most common malignant liver tumor among children. To gain insight into the pathobiology of HB, we performed RNA sequence analysis on 5 patient-derived xenograft lines (HB-243, HB-279, HB-282, HB-284, HB-295) and 1 immortalized cell line (HUH6). Using cultured hepatocytes a...

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Bibliographic Details
Main Authors: Ruth Nousiainen, Katja Eloranta, Noora Isoaho, Stefano Cairo, David B. Wilson, Markku Heikinheimo, Marjut Pihlajoki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
hepatoblastoma
liver tumor
pediatric cancer
ubiquitin
UBE2C
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1170940/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1170940/full

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