Induction of acetyl-LDL receptor activity by phorbol ester in human monocyte cell line THP-1.

Human monocytic cell line THP-1 incubated with as little as 10 ng/ml of phorbol myristate acetate bound and metabolized 1-2 micrograms of Ac-LDL over a 5-h period. In the absence of phorbol treatment, no specific metabolism of Ac-LDL occurred. Optimal levels of receptor were reached after 72 h of ex...

詳細記述

書誌詳細
主要な著者: D P Via, L Pons, D K Dennison, A E Fanslow, F Bernini
フォーマット: 論文
言語:English
出版事項: Elsevier 1989-10-01
シリーズ:Journal of Lipid Research
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S0022227520382304