Cdk5 Phosphorylates a Component of the HDAC Complex and Regulates Histone Acetylation during Neuronal Cell Death

Cyclin-dependent kinase 5 (Cdk5), a member of the cyclin-dependent kinase family, is critical for regulating neural development and neuronal survival. Dysregulation of Cdk5 is associated with abnormal expression of cell cycle-related proteins during neuronal apoptosis. We have previously found that...

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Bibliographic Details
Main Authors: Amy K.Y. Fu, Kwok-Wang Hung, Hovy Ho-Wai Wong, Wing-Yu Fu, Nancy Y. Ip
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2012-03-01
Series:Neurosignals
Subjects:
Online Access:http://www.karger.com/Article/FullText/335158