Mutation analysis of the ERCC4/FANCQ gene in hereditary breast cancer.

Mutation analysis of the ERCC4/FANCQ gene in hereditary breast cancer.

The ERCC4 protein forms a structure-specific endonuclease involved in the DNA damage response. Different cancer syndromes such as a subtype of Xeroderma pigmentosum, XPF, and recently a subtype of Fanconi Anemia, FA-Q, have been attributed to biallelic ERCC4 gene mutations. To investigate whether mo...

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Bibliographic Details
Main Authors: Sandra Kohlhase, Natalia V Bogdanova, Peter Schürmann, Marina Bermisheva, Elza Khusnutdinova, Natalia Antonenkova, Tjoung-Won Park-Simon, Peter Hillemanns, Andreas Meyer, Hans Christiansen, Detlev Schindler, Thilo Dörk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897449?pdf=render

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http://europepmc.org/articles/PMC3897449?pdf=render

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