High expression of CDKN2A is associated with poor prognosis in colorectal cancer and may guide PD-1-mediated immunotherapy

Abstract Background Colorectal cancer (CRC) is one of the most common malignancies worldwide. Immunotherapy targeting the programmed death protein 1(PD-1) and its ligand (PD-L1), is a promising treatment option for many cancers, but has exhibited poor therapeutic efficacy in CRC. This study aimed to...

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Bibliographic Details
Main Authors: Yuying Dong, Mingming Zheng, Xiaoxuan Wang, Chenyue Yu, Tiantian Qin, Xuning Shen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11603-w