Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids

Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids

Abstract Three-dimensional human intestinal organoids (hIO) are widely used as a platform for biological and biomedical research. However, reproducibility and challenges for large-scale expansion limit their applicability. Here, we establish a human intestinal stem cell (ISC) culture method expanded...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Ohman Kwon, Hana Lee, Jaeeun Jung, Ye Seul Son, Sojeong Jeon, Won Dong Yoo, Naeun Son, Kwang Bo Jung, Eunho Choi, In-Chul Lee, Hyung-Jun Kwon, Chuna Kim, Mi-Ok Lee, Hyun-Soo Cho, Dae Soo Kim, Mi-Young Son
Format: Artykuł
Język:English
Wydane: Nature Portfolio 2024-01-01
Seria:Nature Communications
Dostęp online:https://doi.org/10.1038/s41467-024-45103-7

Internet

https://doi.org/10.1038/s41467-024-45103-7

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