An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors
Non-structural protein 3 (nsp3) from all coronaviruses (CoVs) contains a conserved macrodomain, known as Mac1, that has been proposed as a potential therapeutic target for CoVs due to its critical role in viral pathogenesis. Mac1 is an ADP-ribose binding protein and ADP-ribosylhydrolase that promote...
Main Authors: | Joseph J. O’Connor, Dana Ferraris, Anthony R. Fehr |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/12/10/1221 |
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