The many faces of cancer evolution

Summary: Cancer cells acquire genotypic and phenotypic changes over the course of the disease. A minority of these changes enhance cell fitness, allowing a tumor to evolve and overcome environmental constraints and treatment. Cancer evolution is driven by diverse processes governed by different rule...

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Bibliographic Details
Main Authors: Giovanni Ciriello, Luca Magnani
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003710