Deacetylation of CHK2 by SIRT1 protects cells from oxidative stress-dependent DNA damage response
Cancer therapy: Limiting responses to DNA damage Protein interactions that protect cells from excessive responses to DNA damage may help improve cancer treatments. Normal metabolic processes and environmental factors such as exposure to radiation can damage DNA within cells. Excessive responses to s...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-019-0232-4 |