Integrative Analysis Identifies Cell-Type-Specific Genes Within Tumor Microenvironment as Prognostic Indicators in Hepatocellular Carcinoma

Integrative Analysis Identifies Cell-Type-Specific Genes Within Tumor Microenvironment as Prognostic Indicators in Hepatocellular Carcinoma

BackgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, but effective early detection and prognostication methods are lacking. MethodsThe Cox regression model was built to stratify the HCC patients. The single-cell RNA sequencing data analysis and gene set...

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Bibliographic Details
Main Authors: Zi-Li Huang, Bin Xu, Ting-Ting Li, Yong-Hua Xu, Xin-Yu Huang, Xiu-Yan Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
recurrence-free survival
single-cell RNA sequencing
tumor microenvironment
T cell
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.878923/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.878923/full

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