Inhibition of thymic stromal lymphopoietin production by FK3453

To prevent the onset and aggravation of allergic diseases, it is necessary to modulate excessive Th2-type immune responses. It is well accepted that thymic stromal lymphopoietin (TSLP) plays important roles in the change of Th1/Th2 balance to Th2 dominance and would be a druggable target. In this st...

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Bibliographic Details
Main Authors: Ryosuke Segawa, Ryosuke Ishihara, Masahiro Hiratsuka, Noriyasu Hirasawa
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861322000433