Early weaning causes small intestinal atrophy by inhibiting the activity of intestinal stem cells: involvement of Wnt/β-catenin signaling

Early weaning causes small intestinal atrophy by inhibiting the activity of intestinal stem cells: involvement of Wnt/β-catenin signaling

Abstract Background Early weaning and shorter breastfeeding duration are applied by a proportion of young mothers, especially in the social spheres of poverty-stricken areas. Early childhood is a critical period for intestinal development, which is driven by intestinal stem cells (ISCs). However, ho...

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Bibliographic Details
Main Authors: Junquan Tian, Yuying Li, Xuetai Bao, Fan Yang, Xiongzhuo Tang, Qian Jiang, Yulong Yin, Kang Yao
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Early weaning
Intestinal stem cells
Wnt/β-catenin
Intestinal growth
Epithelial regeneration
Online Access:https://doi.org/10.1186/s13287-023-03293-9

Internet

https://doi.org/10.1186/s13287-023-03293-9

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