Integrated network analysis and metabolomics reveal the molecular mechanism of Yinchen Sini decoction in CCl4-induced acute liver injury

Integrated network analysis and metabolomics reveal the molecular mechanism of Yinchen Sini decoction in CCl4-induced acute liver injury

Objective: Yinchen Sini decoction (YCSND), a traditional Chinese medicine (TCM) formula, plays a crucial role in the treatment of liver disease. However, the bioactive constituents and pharmacological mechanisms of action remain unclear. The present study aimed to reveal the molecular mechanism of Y...

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Bibliographic Details
Main Authors: Weiwei Zheng, Chao Shi, Yao Meng, Jian Peng, Yongfei Zhou, Tong Pan, Ke Ning, Qiuhong Xie, Hongyu Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
Yinchen Sini decoction
acute liver injury
network analysis
1 H-NMR
PI3K-AKT
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1221046/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1221046/full

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