Identification of Targets from LRRK2 Rescue Phenotypes

Identification of Targets from LRRK2 Rescue Phenotypes

Parkinson’s disease (PD) is an age-dependent neurodegenerative condition. Leucine-rich repeat kinase 2 (LRRK2) mutations are the most frequent cause of sporadic and autosomal dominant PD. The exact role of LRRK2 protective variants (R1398H, N551K) together with a pathogenic mutant (G2019S) in aging...

Full description

Bibliographic Details
Main Authors: Joanne Toh, Ling Ling Chua, Patrick Ho, Edwin Sandanaraj, Carol Tang, Hongyan Wang, Eng King Tan
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
neurodegeneration
Parkinson’s disease
RNA sequencing
<i>Drosophila melanogaster</i>
LRRK2
Online Access:https://www.mdpi.com/2073-4409/10/1/76

Internet

https://www.mdpi.com/2073-4409/10/1/76

Similar Items