Characterisation of insomnia as an environmental risk factor for asthma via Mendelian randomization and gene environment interaction

Abstract Asthma is a complex disease that is reportedly associated with insomnia. However, the causal directionality of this association is still unclear. We used asthma and insomnia-associated single nucleotide polymorphisms (SNPs) and genome-wide association study (GWAS) summary statistics to test...

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Bibliographic Details
Main Authors: Dong Jun Kim, Tae-Woong Ha, Hae Un Jung, Eun Ju Baek, Won Jun Lee, Han Kyul Kim, Ji-One Kang, Sungho Won, Ji Eun Lim, Bermseok Oh
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01291-6