Double Positive CD4<sup>+</sup>CD8<sup>+</sup> (DP) T-Cells Display Distinct Exhaustion Phenotype in Chronic Hepatitis C

Double Positive CD4<sup>+</sup>CD8<sup>+</sup> (DP) T-Cells Display Distinct Exhaustion Phenotype in Chronic Hepatitis C

In chronic hepatitis C (CHC), characterized by exhaustion of T-cell function, increased frequencies of double-positive (DP) (CD4<sup>+</sup>CD8<sup>+</sup>) cells are present in peripheral blood. We compared the exhaustion phenotype between DP and single positive (SP) T-cells...

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Bibliographic Details
Main Authors: Anna Maria Kochanowicz, Sylwia Osuch, Hanna Berak, Aleksandra Kumorek, Kamila Caraballo Cortés
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
CD4<sup>+</sup>CD8<sup>+</sup> double positive (DP) T-cells
hepatitis C virus
antiviral treatment
DAA
T-cell exhaustion
PD-1
Online Access:https://www.mdpi.com/2073-4409/12/10/1446

Internet

https://www.mdpi.com/2073-4409/12/10/1446

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