Phosphorylation provides a negative mode of regulation for the yeast Rab GTPase Sec4p.

The Rab family of Ras-related GTPases are part of a complex signaling circuitry in eukaryotic cells, yet we understand little about the mechanisms that underlie Rab protein participation in such signal transduction networks, or how these networks are integrated at the physiological level. Reversible...

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Bibliographic Details
Main Authors: Christopher D Heger, Christiane D Wrann, Ruth N Collins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171412?pdf=render