Neural reprogramming via microRNAs: the new kid on the p53-deficient block

We recently reported a novel role for nerve-cancer crosstalk, demonstrating that tumor protein p53 (TP53) deficiency in head and neck squamous cell carcinoma leads to a decrease in miR-34a in tumor-shed vesicles. This directed sensory nerve reprogramming in the tumor microenvironment which enhanced...

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Bibliographic Details
Main Authors: Deborah A. Silverman, George A. Calin, Jeffrey N. Myers, Moran Amit
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1756723