Assessment of RT-qPCR normalization strategies for accurate quantification of extracellular microRNAs in murine serum.

Extracellular microRNAs (miRNAs) are under investigation as minimally-invasive biomarkers for a wide range of disease conditions. We have recently shown in a mouse model of the progressive muscle-wasting condition Duchenne muscular dystrophy (DMD) that a set of highly elevated serum miRNAs reflects...

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Bibliographic Details
Main Authors: Thomas C Roberts, Anna M L Coenen-Stass, Matthew J A Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3929707?pdf=render