Cepharanthine Alleviates DSS-Induced Ulcerative Colitis via Regulating Aconitate Decarboxylase 1 Expression and Macrophage Infiltration

Cepharanthine Alleviates DSS-Induced Ulcerative Colitis via Regulating Aconitate Decarboxylase 1 Expression and Macrophage Infiltration

Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid from tubers of Stephania, protects against some inflammatory diseases. Aconitate decarboxylase 1 (ACOD1) is also known as immune-responsive gene 1 (IRG1), which plays an important immunometabolism role in inflammatory diseases by mediating the pr...

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Bibliographic Details
Main Authors: Min-Na Zhang, Rui Xie, Hong-Gang Wang, Xin Wen, Jing-Yi Wang, Le He, Meng-Hui Zhang, Xiao-Zhong Yang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Cepharanthine
gut microbiota
colitis
ACOD1
macrophage
Online Access:https://www.mdpi.com/1420-3049/28/3/1060

Internet

https://www.mdpi.com/1420-3049/28/3/1060

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