Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

<p>Abstract</p> <p>Background</p> <p>Common single-nucleotide polymorphisms (SNPs) in ten chromosomal loci have been shown to predispose to colorectal cancer (CRC) in genome-wide association studies. A plausible biological mechanism of CRC susceptibility associated with...

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Main Authors: Houlston Richard S, Tomlinson Ian PM, Järvinen Heikki, Mecklin Jukka-Pekka, Li Yilong, Tuupanen Sari, Niittymäki Iina, Karhu Auli, Aaltonen Lauri A
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/23

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http://www.biomedcentral.com/1471-2350/12/23

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