Transcriptional control of an essential ribozyme in Drosophila reveals an ancient evolutionary divide in animals.

Ribonuclease P (RNase P) is an essential enzyme required for 5'-maturation of tRNA. While an RNA-free, protein-based form of RNase P exists in eukaryotes, the ribonucleoprotein (RNP) form is found in all domains of life. The catalytic component of the RNP is an RNA known as RNase P RNA (RPR). E...

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Bibliographic Details
Main Authors: Sathiya N Manivannan, Lien B Lai, Venkat Gopalan, Amanda Simcox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4287351?pdf=render