The Contentious History of Sirtuin Debates
The sirtuins are highly conserved enzyme homologues of the yeast Sir2, with activities of NAD+ dependent deacetylase and/or mono ADP ribosyltransferase. A long line of evidence has implicated sirtuins in regulating the aging process of yeast, worms, flies, and rodents. Moreover, much work has been p...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Rambam Health Care Campus
2012-10-01
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| Series: | Rambam Maimonides Medical Journal |
| Subjects: | |
| Online Access: | http://rmmj.org.il/Pages/ArticleHTM.aspx?manuId=237 |