Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs

Induced pluripotent stem cells (iPSCs) have enormous potential in producing human tissues endlessly. We previously reported that type V collagen (COL5), a pancreatic extracellular matrix protein, promotes islet development and maturation from iPSCs. In this study, we identified a bioactive peptide d...

Full description

Bibliographic Details
Main Authors: Emma S Heaton, Ming Hu, Tianzheng Liu, Huang Hui, Yinfei Tan, Kaiming Ye, Sha Jin
Format: Article
Language:English
Published: SAGE Publishing 2023-07-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231185858