Optogenetic control of gut bacterial metabolism to promote longevity

Optogenetic control of gut bacterial metabolism to promote longevity

Gut microbial metabolism is associated with host longevity. However, because it requires direct manipulation of microbial metabolism in situ, establishing a causal link between these two processes remains challenging. We demonstrate an optogenetic method to control gene expression and metabolite pro...

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Bibliographic Details
Main Authors: Lucas A Hartsough, Mooncheol Park, Matthew V Kotlajich, John Tyler Lazar, Bing Han, Chih-Chun J Lin, Elena Musteata, Lauren Gambill, Meng C Wang, Jeffrey J Tabor
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
longevity
aging
optogenetics
bacteria-host interaction
mitochondria
Online Access:https://elifesciences.org/articles/56849

Internet

https://elifesciences.org/articles/56849

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