Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions
Macroautophagy, a quality control mechanism, is an evolutionarily conserved pathway of lysosomal degradation of protein aggregates, pathogens, and damaged organelles. As part of its vital homeostatic role, macroautophagy deregulation is associated with various human disorders, including neurodegener...
Main Authors: | João Duarte Magalhães, Lígia Fão, Rita Vilaça, Sandra Morais Cardoso, Ana Cristina Rego |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/9/11/1625 |
Similar Items
-
Mitophagy: A potential therapeutic target for insulin resistance
by: Peng Ning, et al.
Published: (2022-08-01) -
A Healthy Heart and a Healthy Brain: Looking at Mitophagy
by: Hongke Luo, et al.
Published: (2020-05-01) -
Autophagy and autophagy‐related molecules in neurodegenerative diseases
by: Changsong Dou, et al.
Published: (2023-02-01) -
Cogs in the autophagic machine—equipped to combat dementia-prone neurodegenerative diseases
by: Sholto de Wet, et al.
Published: (2023-08-01) -
Autophagy and Mitophagy as Essential Components of Atherosclerosis
by: Anastasia V. Poznyak, et al.
Published: (2021-02-01)