A DFX-based iron nanochelator for cancer therapy

Iron as an essential element, is involved in various cellular functions and maintaining cell viability, cancer cell is more dependent on iron than normal cell due to its chief characteristic of hyper-proliferation. Despite that some of the iron chelators exhibited potent and broad antitumor activity...

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Bibliographic Details
Main Authors: Peng Liu, Qiang Wang, Kuan Li, Bo Bi, Ying-Fei Wen, Miao-Juan Qiu, Jing Zhao, Bin-Bin Li, Chang-Hua Zhang, Yu-Long He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1078137/full