MPrESS: An R-Package for Accurately Predicting Power for Comparisons of 16S rRNA Microbiome Taxa Distributions including Simulation by Dirichlet Mixture Modeling

MPrESS: An R-Package for Accurately Predicting Power for Comparisons of 16S rRNA Microbiome Taxa Distributions including Simulation by Dirichlet Mixture Modeling

Deep sequencing has revealed that the 16S rRNA gene composition of the human microbiome can vary between populations. However, when existing data are insufficient to address the desired study questions due to limited sample sizes, Dirichlet mixture modeling (DMM) can simulate 16S rRNA gene predictio...

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Bibliographic Details
Main Authors: Thomas H. Clarke, Chris Greco, Lauren Brinkac, Karen E. Nelson, Harinder Singh
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Microorganisms
Subjects:
dirichlet mixture modeling
16S rRNA gene sequencing
power calculations
sample size estimates
human microbiome
forensics
Online Access:https://www.mdpi.com/2076-2607/11/5/1166

Internet

https://www.mdpi.com/2076-2607/11/5/1166

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