Activated Platelets Autocrine 5-Hydroxytryptophan Aggravates Sepsis-Induced Acute Lung Injury by Promoting Neutrophils Extracellular Traps Formation
Excessive neutrophil extracellular trap (NET) formation is an important contributor to sepsis-induced acute lung injury (ALI). Recent reports indicate that platelets can induce neutrophil extracellular trap formation. However, the specific mechanism remains unclear. Tph1 gene, which encodes the rate...
Main Authors: | Yumeng Huang, Qian Ji, Yanyan Zhu, Shengqiao Fu, Shuangwei Chen, Liangmei Chu, Yongfei Ren, Yue Wang, Xuan Lei, Jia Gu, Ningzheng Tai, Dadong Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-01-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.777989/full |
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