Notch Signaling-Modified Mesenchymal Stem Cell Patch Improves Left Ventricular Function via Arteriogenesis Induction in a Rat Myocardial Infarction Model

Notch Signaling-Modified Mesenchymal Stem Cell Patch Improves Left Ventricular Function via Arteriogenesis Induction in a Rat Myocardial Infarction Model

For ischemic cardiomyopathy (ICM) with limited therapeutic options, the induction of arteriogenesis has the potential to improve cardiac function through major restoration of blood flow. We hypothesized that transplantation of a Notch signaling-modified mesenchymal stem cell (SB623 cell) patch would...

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Bibliographic Details
Main Authors: Shusaku Maeda, Takuji Kawamura, Dai Chida, Kazuo Shimamura, Koichi Toda, Akima Harada, Yoshiki Sawa, Shigeru Miyagawa
Format: Article
Language:English
Published: SAGE Publishing 2023-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897231154580

Internet

https://doi.org/10.1177/09636897231154580

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