Symmetrical Heterocyclic Cage Skeleton: Synthesis, Urease Inhibition Activity, Kinetic Mechanistic Insight, and Molecular Docking Analyses
The present study focuses on the design and synthesis of a cage-like organic skeleton containing two triazole rings jointed via imine linkage. These molecules can act as urease inhibitors. The in-vitro urease inhibition screening results showed that the combination of the two triazole skeleton in th...
Main Authors: | Muhammad Hanif, Fariha Kanwal, Muhammad Rafiq, Mubashir Hassan, Muhammad Mustaqeem, Sung-Yum Seo, Yunlong Zhang, Changrui Lu, Ting Chen, Muhammad Saleem |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/24/2/312 |
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