Effect of Co-administration of Bumetanide and Phenobarbital on Seizure Attacks in Temporal Lobe Epilepsy

Introduction: The resistance of temporal lobe epilepsy to classic drugs is thought to be due to disruption in the excitation/inhibition of this pathway. Two chloride transporters, NKCC1 and KCC2, are expressed differently for the excitatory state of Gamma-Amino Butyric Acid (GABA). The present study...

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Main Authors: Reza Rahmanzadeh, Soraya Mehrabi, Mahmood Barati, Milad Ahmadi, Fereshteh Golab, Sareh Kazmi, Mohammad Taghi Joghataei, Morteza Seifi, Mazaher Gholipourmalekabadi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2018-11-01
Series:Basic and Clinical Neuroscience
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Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-998-1&slc_lang=en&sid=1