TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/β-catenin pathway

TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/β-catenin pathway

Abstract Background Esophageal carcinoma is the eighth prevalent malignancy and ranks the sixth in carcinoma-related death worldwide. Tumor necrosis factor-α-induced protein-8 like-2 (TIPE2) has been identified as a tumor suppressor in multiple carcinomas. However, its roles and molecular mechanisms...

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Bibliographic Details
Main Authors: Linan Zhu, Xudong Zhang, Xiaorui Fu, Zhaoming Li, Zhenchang Sun, Jingjing Wu, Xinhua Wang, Feng Wang, Xiangke Li, Songtao Niu, Mengjie Ding, Zhenzhen Yang, Wanqiu Yang, Meifeng Yin, Lei Zhang, Mingzhi Zhang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Translational Medicine
Subjects:
Esophageal carcinoma
TIPE2
Proliferation
Tumorigenesis
Wnt/β-catenin pathway
Online Access:http://link.springer.com/article/10.1186/s12967-018-1383-0

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http://link.springer.com/article/10.1186/s12967-018-1383-0

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