Unveiling the biology of defective viral genomes in vitro and in vivo: implications for gene expression and pathogenesis of coronavirus

Abstract Background Defective viral genome (DVG) is a truncated version of the full-length virus genome identified in most RNA viruses during infection. The synthesis of DVGs in coronavirus has been suggested; however, the fundamental characteristics of coronavirus DVGs in gene expression and pathog...

Full description

Bibliographic Details
Main Authors: Ching-Hung Lin, BoJia Chen, Day-Yu Chao, Feng-Cheng Hsieh, Chun-Chun Yang, Hsuan-Wei Hsu, Hon-Man-Herman Tam, Hung-Yi Wu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-023-02189-7