A functional role for Serum Amyloid A in the molecular regulation of autophagy in breast cancer
It has been established that the acute phase protein, Serum amyloid A (SAA), which is usually synthesized by the liver, is also synthesized by cancer cells and cancer-associated cells in the tumor microenvironment. SAA also activates modulators of autophagy, such as the PI3K/Akt and MAPK signaling p...
Main Authors: | Manisha du Plessis, Tanja Andrea Davis, Daniel Wilhelm Olivier, Willem Johan Simon de Villiers, Anna-Mart Engelbrecht |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1000925/full |
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