Adhesion molecules and cerebral microvascular hemodynamic abnormalities in sickle cell disease
Cerebrovascular abnormalities are a common feature of sickle cell disease that may be associated with risk of vaso-occlusive pain crises, microinfarcts, and cognitive impairment. An activated endothelium and adhesion factors, VCAM-1 and P-selectin, are implicated in sickle cell vasculopathy, includi...
Main Authors: | Noor Mary Abi Rached, Oluwabukola T. Gbotosho, David R. Archer, Jayre A. Jones, Morgan S. Sterling, Hyacinth I. Hyacinth |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.976063/full |
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