Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series

Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series

Abstract Background The tumor-agnostic indication of immune checkpoint inhibitors to treat cancers with mismatch repair deficiency (dMMR)/microsatellite instability (MSI) increased the demand for such tests beyond Lynch syndrome. International guideline recommendations accept immunohistochemistry (I...

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Bibliographic Details
Main Authors: Maja L. Nádorvári, István Kenessey, András Kiss, Tamás Barbai, Janina Kulka, Erzsébet Rásó, József Tímár
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Mismatch repair deficiency
Immunohistochemistry
Microsatellite instability
Pentaplex PCR
Malignant tumors
Online Access:https://doi.org/10.1186/s12967-024-04960-y

Internet

https://doi.org/10.1186/s12967-024-04960-y

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