Crocin mitigates atherosclerotic progression in LDLR knockout mice by hepatic oxidative stress and inflammatory reaction reduction, and intestinal barrier improvement and gut microbiota modulation
Crocin has a protective effect on neurodegenerative disease, but whether crocin can prevent atherosclerosis remains unclear. The present study aimed to explore the possible anti-atherosclerotic mechanism of crocin in LDLR-/- mice. Mice were fed an atherogenic high-fat/cholesterol diet and concomitan...
Main Authors: | Shufen Han, Ruijuan Song, Yifei Cao, Xiao Yan, Hui Gao, Fuzhi Lian |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464622002912 |
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