Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) as A Therapeutical Target in Type-2 Diabetes Mellitus: A Review

BACKGROUND: Increasing free radicals and oxidative stress due to chronic hyperglycemia in type-2 diabetes mellitus (DM) promotes the activity of endogenic antioxidative genes. Nuclear factor erythroid 2-related factor 2 (Nrf2) expression and activity are important to regulate the production of endog...

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Bibliographic Details
Main Author: Asri Hendrawati
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2017-08-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/311