Expression of Translocator Protein and [18F]-GE180 Ligand Uptake in Multiple Sclerosis Animal Models

Expression of Translocator Protein and [18F]-GE180 Ligand Uptake in Multiple Sclerosis Animal Models

Positron emission tomography (PET) ligands targeting the translocator protein (TSPO) represent promising tools to visualize neuroinflammation in multiple sclerosis (MS). Although it is known that TSPO is expressed in the outer mitochondria membrane, its cellular localization in the central nervous s...

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Bibliographic Details
Main Authors: Anne Nack, Matthias Brendel, Julia Nedelcu, Markus Daerr, Stella Nyamoya, Cordian Beyer, Carola Focke, Maximilian Deussing, Chloé Hoornaert, Peter Ponsaerts, Christoph Schmitz, Peter Bartenstein, Axel Rominger, Markus Kipp
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cells
Subjects:
multiple sclerosis
cuprizone
TSPO
PET
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/8/2/94

Internet

https://www.mdpi.com/2073-4409/8/2/94

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