Nicotinamide mononucleotide (NMN) alleviates the poly(I:C)-induced inflammatory response in human primary cell cultures

Abstract NMN is the direct precursor of nicotinamide adenine dinucleotide (NAD+) and is considered as a key factor for increasing NAD+ levels and mitochondrial activity in cells. In this study, based on transcriptome analysis, we showed that NMN alleviates the poly(I:C)-induced inflammatory response...

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Bibliographic Details
Main Authors: Hitomi Sano, Anton Kratz, Taiko Nishino, Haruna Imamura, Yuki Yoshida, Noriaki Shimizu, Hiroaki Kitano, Ayako Yachie
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38762-x