Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.

Inversin is a ciliary protein that critically regulates developmental processes and tissue homeostasis in vertebrates, partly through the degradation of Dishevelled (Dvl) proteins to coordinate Wnt signaling in planar cell polarity (PCP). Here, we investigated the role of Inversin in coordinating ce...

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Bibliographic Details
Main Authors: Iben R Veland, Rodrick Montjean, Lorraine Eley, Lotte B Pedersen, Albrecht Schwab, Judith Goodship, Karsten Kristiansen, Stine F Pedersen, Sophie Saunier, Søren T Christensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620528?pdf=render