Distinct Gene Expression Profiles in Viable Hepatocellular Carcinoma Treated With Liver-Directed Therapy

Distinct Gene Expression Profiles in Viable Hepatocellular Carcinoma Treated With Liver-Directed Therapy

BackgroundHepatocellular carcinoma is a heterogeneous tumor that accumulates a mutational burden and dysregulated signaling pathways that differ from early to advanced stages. Liver transplant candidates with early-stage hepatocellular carcinoma (HCC) undergo liver-directed therapy (LDT) to delay di...

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Bibliographic Details
Main Authors: Kelley G. Núñez, Tyler Sandow, Meredith A. Lakey, Daniel Fort, Ari J. Cohen, Paul T. Thevenot
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
tumor microenvironment
transcriptomics
liver transplantation
intrahepatic spread
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.809860/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.809860/full

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