Mosaic RBD Nanoparticles Elicit Protective Immunity Against Multiple Human Coronaviruses in Animal Models

Mosaic RBD Nanoparticles Elicit Protective Immunity Against Multiple Human Coronaviruses in Animal Models

Abstract To combat SARS‐CoV‐2 variants and MERS‐CoV, as well as the potential re‐emergence of SARS‐CoV and spillovers of sarbecoviruses, which pose a significant threat to global public health, vaccines that can confer broad‐spectrum protection against betacoronaviruses (β‐CoVs) are urgently needed....

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Bibliographic Details
Main Authors: Yanjun Zhang, Jing Sun, Jian Zheng, Suxiang Li, Haiyue Rao, Jun Dai, Zhaoyong Zhang, Yanqun Wang, Donglan Liu, Zhao Chen, Wei Ran, Airu Zhu, Fang Li, Qihong Yan, Yiliang Wang, Kuai Yu, Shengnan Zhang, Dong Wang, Yanhong Tang, Banghui Liu, Linling Cheng, Jiandong Huo, Stanley Perlman, Jingxian Zhao, Jincun Zhao
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
mosaic RBD nanoparticle vaccine coronavirus
Online Access:https://doi.org/10.1002/advs.202303366

Internet

https://doi.org/10.1002/advs.202303366

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