CircSFMBT2-OA alleviates chondrocyte apoptosis and extracellular matrix degradation through repressing NF-κB/NLRP3 inflammasome activation

CircSFMBT2-OA alleviates chondrocyte apoptosis and extracellular matrix degradation through repressing NF-κB/NLRP3 inflammasome activation

Background: Intra-articular inflammation and cartilage degradation are the major pathological characteristics of osteoarthritis (OA). Mounting studies have revealed that circular RNAs (circRNAs) act as an important regulatory role in inflammatory diseases and are frequently dys-expressed in OA carti...

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Bibliographic Details
Main Authors: Axiang He, Yaru Liu, Renbo Zhang, Yanjie Mao, Wanjun Liu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Osteoarthritis
circSFMBT2-OA
Inflammation
Chondrocyte injury
NLRP3
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023045206

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http://www.sciencedirect.com/science/article/pii/S2405844023045206

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