Perinatal Propionate Supplementation Protects Adult Male Offspring from Maternal Chronic Kidney Disease-Induced Hypertension

Perinatal Propionate Supplementation Protects Adult Male Offspring from Maternal Chronic Kidney Disease-Induced Hypertension

Emerging evidence supports that early-life disturbance of gut microbiota has an impact on adult disease in later life. Offspring hypertension can be programmed by maternal chronic kidney disease (CKD). Conversely, perinatal use of gut microbiota-targeted therapy has been implemented to reverse progr...

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Bibliographic Details
Main Authors: You-Lin Tain, Chih-Yao Hou, Guo-Ping Chang-Chien, Su-Fan Lin, Chien-Ning Hsu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Nutrients
Subjects:
gut microbiota
short-chain fatty acid
developmental origins of health and disease (DOHaD)
propionate
hypertension
chronic kidney disease
Online Access:https://www.mdpi.com/2072-6643/14/16/3435

Internet

https://www.mdpi.com/2072-6643/14/16/3435

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