Transcription factor binding sites prediction based on modified nucleosomes.

In computational methods, position weight matrices (PWMs) are commonly applied for transcription factor binding site (TFBS) prediction. Although these matrices are more accurate than simple consensus sequences to predict actual binding sites, they usually produce a large number of false positive (FP...

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Bibliographic Details
Main Authors: Mohammad Talebzadeh, Fatemeh Zare-Mirakabad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931712?pdf=render