Molecular mechanisms of TGFβ-mediated EMT of retinal pigment epithelium in subretinal fibrosis of age-related macular degeneration

Age-related macular degeneration (AMD) is one of the leading causes of blindness in the elderly, affecting the macula of the retina and resulting in vision loss. There are two types of AMD, wet and dry, both of which cause visual impairment. Wet AMD is called neovascular AMD (nAMD) and is characteri...

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Bibliographic Details
Main Authors: Fumiaki Higashijima, Mina Hasegawa, Takuya Yoshimoto, Yuka Kobayashi, Makiko Wakuta, Kazuhiro Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Ophthalmology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2022.1060087/full