Catalyst free one pot three components synthesis of 2-iminothiazoles from nitroepoxides and thiourea
Abstract Nitroepoxides were introduced as efficient substrates for the one-pot three-component synthesis of 2-iminothiazoles under catalyst-free conditions. Reaction of amines, isothiocyanates, and nitroepoxides in THF at 10–15 °C afforded corresponding 2-iminothiazoles in high to excellent yields....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-30243-5 |