Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer

Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer

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Low-density lipoprotein (LDL) receptors are overexpressed in most neoplastic cell lines and provide a mechanism for the internalization and concentration of drug-laden nanoemulsions that bind to these receptors. The aim of the present study was to determine whether the administration of standard che...

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Bibliographic Details
Main Authors: L.A. Pires, R. Hegg, F.R. Freitas, E.R. Tavares, C.P. Almeida, E.C. Baracat, R.C. Maranhão
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Breast cancer
Lipoproteins
LDL receptor
LRP-1 receptor
Chemotherapy
Nanoemulsion
Drug delivery
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600012&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600012&lng=en&tlng=en

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